Microscopic Anatomy of Skeletal Muscle Activity



  1. Skeletal muscle fibers are also known as __________


  1. Name the repeating light and dark bands visible on the surfaces of skeletal muscle fibers


  1. Name the protein-filled cytoplasm of a myofiber


  1. In other cells it is called the cell membrane; what is it called in skeletal muscle?


  1. What is a bundle of skeletal muscle fibers called?


  1. Name the membranes:
    1. Around whole muscle


    1. Around fascicles


    1. Around muscle fibers (cells)


  1. Are muscles vascular or avascular?


  1. Name the elongated bundles of contractile proteins that fill the cytoplasm of myofibers (muscle cells)


  1. Name the flattened tubules that surround the myofibrils


  1. Name the ions that are concentrated in the terminal cisternae while skeletal muscle fibers are at rest


  1. What is a thin filament composed of and what does it look like?


  1. What covers the myosin binding sites when the muscle fiber is at rest?


  1. How does the protein troponin assist in the contraction of a sarcomere?


  1. Each muscle fiber is stimulated by what type of neuron?


  1. What makes up a neuromuscular junction?


  1. Explain a motor unit.


  1. The size of a motor unit varies from __________ in the precise muscles to over a _____ fibers in the powerful muscles.


  1. Each terminal branch runs along a shallow groove in the muscle fiber __________


  1. Name the tips of the terminal branches of the axon


  1. Define synaptic cleft.


  1. Name the chemical that diffuses across the synaptic cleft to bind on receptors in the sarcolemma


  1. Where are the acetylcholine receptors located?


  1. What happens when ACh binds with the receptor?


  1. Which ion enters a muscle fiber and which ion exits the muscle fiber?


  1. What ion goes through open channels to depolarize the myofiber?


  1. How does the signal spread into the myofiber.


  1. When the signal reaches the inside of the myofiber it releases what ions?


  1. What molecule does the calcium bind to?




  1. Read the tutorials and summarize the skeletal muscle fiber contraction physiology in a few sentences from the EC Coupling to the Contraction Cycle.



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